eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
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4/2011
vol. 36
 
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Review paper
Adverse reactions caused by metabisulfites, with particular emphasis on contact allergy – a study of 396 patients and review of literature

Adriana Polańska
,
Dorota Jenerowicz
,
Maria Żmudzińska
,
Aleksandra Dańczak-Pazdrowska
,
Magdalena Czarnecka-Operacz
,
Wojciech Silny

(Centr Eur J Immunol 2011; 36 (4): 293-297)
Online publish date: 2011/12/24
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Sulfur compounds, especially metabisulfites, are ubiquitous, widely used preservatives for many applications. They are commonly used in food as well as in pharmaceutical and cosmetic industries. There are numerous reports indicating the important role of metabisulfites as occupational allergens, causing allergic contact dermatitis mainly involving hands. The aim of this paper is to review the recent data on adverse reactions caused by these compounds with particular emphasis on contact allergy. The authors also present their own results of patch tests with sodium metabisulfite.
keywords:

metabisulfites, contact allergy to sulfites, anesthetics

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